Funobactam

Funobactam (XNW4107) is a β-lactamase inhibitor, can be used for researching anti-bacteria[1].

Product Specifications

CAS Number

[2365454-12-0]

Product Name Alternative

XNW4107

UNSPSC

12352005

Target

Bacterial; Beta-lactamase

Type

Reference compound

Related Pathways

Anti-infection

Applications

COVID-19-immunoregulation

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/funobactam.html

Purity

99.47

Solubility

DMSO : 25 mg/mL (ultrasonic)

Smiles

O=S(ON1[C@@H]2C3(CC3)C[C@](C4=NN=C([C@@]5([H])NC(N)=NC5)O4)([H])[N@](C1=O)C2)(O)=O

Molecular Formula

C13H17N7O6S

Molecular Weight

399.38

References & Citations

[1]International Nonproprietary Names for Pharmaceutical Substances (INN) . WHO Drug Information, Vol. 36, No. 2, 2022.|[2]Song Zhang, et al. Role of β-Lactamase Inhibitors as Potentiators in Antimicrobial Chemotherapy Targeting Gram-Negative Bacteria. Antibiotics (Basel) . 2024 Mar 15;13 (3) :260.|[3]Andrew J Fratoni, et al. Imipenem/funobactam (formerly XNW4107) in vivo pharmacodynamics against serine carbapenemase-producing Gram-negative bacteria: a novel modelling approach for time-dependent killing. J Antimicrob Chemother. 2023 Aug 10;78 (9) :2343–2353.