GRL-1720 (TFA)
GRL-1720 TFA is a potent inhibitor of SARS-CoV-2 Mpro with an EC50 value of 15 μM. GRL-1720 TFA shows anti-SARS-CoV2 activity[1].
Product Specifications
UNSPSC
12352005
Target
SARS-CoV
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-anti-virus
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/grl-1720-tfa.html
Purity
98.94
Solubility
DMSO : 50 mg/mL (ultrasonic)
Smiles
O=C(C1=C2CCNC2=CC=C1)OC3=CC(Cl)=CN=C3.OC(C(F)(F)F)=O
Molecular Formula
C16H12ClF3N2O4
Molecular Weight
388.73
References & Citations
[1]Hattori SI, et al. A small molecule compound with an indole moiety inhibits the main protease of SARS-CoV-2 and blocks virus replication. Nat Commun. 2021 Jan 28;12 (1) :668.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, sealed storage, away from moisture)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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