Squalamine lactate
Squalamine lactate is an aminosterol compound discovered in the tissues of the dogfish shark, with antimicrobial activity, and used for the treatment of neovascular age-related macular degeneration.
Product Specifications
CAS Number
320725-47-1
Product Name Alternative
MSI-1256F
UNSPSC
12352211
Target
Bacterial
Type
Natural Products
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection; Cardiovascular Disease; Cancer
Assay Protocol
https://www.medchemexpress.com/Squalamine_lactate.html
Purity
98.42
Solubility
DMSO : ≥ 36.66 mg/mL
Smiles
NCCCCNCCCN[C@H]1CC[C@@]2(C)[C@](C[C@@H](O)[C@]3([H])[C@]2([H])CC[C@@]4(C)[C@@]3([H])CC[C@]4([H])[C@H](C)CC[C@@H](OS(=O)(O)=O)C(C)C)([H])C1.C[C@@H](C(O)=O)O
Molecular Formula
C37H71N3O8S
Molecular Weight
718.04
References & Citations
[1]Hussain RM, et al. Emerging vascular endothelial growth factor antagonists to treat neovascular age-related macular degeneration. Expert Opin Emerg Drugs. 2017 Sep;22 (3) :235-246.|[2]Emerson MV, et al. Current and emerging therapies for the treatment of age-related macular degeneration. Clin Ophthalmol. 2008 Jun;2 (2) :377-88.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture)
Scientific Category
Natural Products
Clinical Information
Phase 3
Available Sizes
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