Squalamine lactate

Squalamine lactate is an aminosterol compound discovered in the tissues of the dogfish shark, with antimicrobial activity, and used for the treatment of neovascular age-related macular degeneration.

Product Specifications

CAS Number

[320725-47-1]

Product Name Alternative

MSI-1256F

UNSPSC

12352211

Target

Bacterial

Type

Natural Products

Related Pathways

Anti-infection

Applications

COVID-19-immunoregulation

Field of Research

Infection; Cardiovascular Disease; Cancer

Assay Protocol

https://www.medchemexpress.com/Squalamine_lactate.html

Purity

98.42

Solubility

DMSO : ≥ 36.66 mg/mL

Smiles

NCCCCNCCCN[C@H]1CC[C@@]2(C)[C@](C[C@@H](O)[C@]3([H])[C@]2([H])CC[C@@]4(C)[C@@]3([H])CC[C@]4([H])[C@H](C)CC[C@@H](OS(=O)(O)=O)C(C)C)([H])C1.C[C@@H](C(O)=O)O

Molecular Formula

C37H71N3O8S

Molecular Weight

718.04

References & Citations

[1]Hussain RM, et al. Emerging vascular endothelial growth factor antagonists to treat neovascular age-related macular degeneration. Expert Opin Emerg Drugs. 2017 Sep;22 (3) :235-246.|[2]Emerson MV, et al. Current and emerging therapies for the treatment of age-related macular degeneration. Clin Ophthalmol. 2008 Jun;2 (2) :377-88.