N-Methyl-DL-aspartic acid

N-Methyl-DL-aspartic acid is a glutamate analogue and a NMDA receptor agonist and can be used for neurological diseases research[1][2].

Product Specifications

CAS Number

[17833-53-3]

UNSPSC

12352211

Hazard Statement

H315, H319, H335

Target

IGluR

Type

Reference compound

Related Pathways

Membrane Transporter/Ion Channel; Neuronal Signaling

Applications

Neuroscience-Neurodegeneration

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/n-methyl-dl-aspartic-acid.html

Concentration

10mM

Purity

98.0

Solubility

DMSO : 4.17 mg/mL (ultrasonic; warming; heat to 60°C) |H2O : 16.67 mg/mL (ultrasonic)

Smiles

O=C(O)CC(C(O)=O)NC

Molecular Formula

C5H9NO4

Molecular Weight

147.13

Precautions

H315, H319, H335

References & Citations

[1]G R Lauretti, et al. The activity of opioid analgesics in seizure models utilizing N-methyl-DL-aspartic acid, kainic acid, bicuculline and pentylenetetrazole. Neuropharmacology. 1994 Feb;33 (2) :155-60.|[2]S J Czuczwar, et al. Antagonism of N-methyl-D, L-aspartic acid-induced convulsions by antiepileptic drugs and other agents. Eur J Pharmacol. 1985 Feb 5;108 (3) :273-80