N-Methyl-DL-aspartic acid
N-Methyl-DL-aspartic acid is a glutamate analogue and a NMDA receptor agonist and can be used for neurological diseases research[1][2].
Product Specifications
CAS Number
17833-53-3
UNSPSC
12352211
Hazard Statement
H315, H319, H335
Target
IGluR
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel; Neuronal Signaling
Applications
Neuroscience-Neurodegeneration
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/n-methyl-dl-aspartic-acid.html
Concentration
10mM
Purity
98.0
Solubility
DMSO : 4.17 mg/mL (ultrasonic; warming; heat to 60°C) |H2O : 16.67 mg/mL (ultrasonic)
Smiles
O=C(O)CC(C(O)=O)NC
Molecular Formula
C5H9NO4
Molecular Weight
147.13
Precautions
H315, H319, H335
References & Citations
[1]G R Lauretti, et al. The activity of opioid analgesics in seizure models utilizing N-methyl-DL-aspartic acid, kainic acid, bicuculline and pentylenetetrazole. Neuropharmacology. 1994 Feb;33 (2) :155-60.|[2]S J Czuczwar, et al. Antagonism of N-methyl-D, L-aspartic acid-induced convulsions by antiepileptic drugs and other agents. Eur J Pharmacol. 1985 Feb 5;108 (3) :273-80
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
NMDA Receptor
Available Sizes
Frequently Asked Questions
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