FAS/CD95 Polyclonal Antibody
Product Specifications
Background
Fas (CD95/APO-1) is a transmembrane glycoprotein belonging to the tumor necrosis factor (TNF) receptor superfamily. It can mediate apoptosis by ligation with an agonistic anti-Fas antibody or Fas ligand. Stimulation of Fas results in the aggregation of its intracellular death domains, leading to the formation of the death-inducing signaling complex (DISC) . FAS-mediated apoptosis may have a role in the induction of peripheral tolerance, in the antigen-stimulated suicide of mature T-cells, or both.
Abbreviation
FAS
UniProt
P25446
Host
Rabbit
Reactivity
Human
Immunogen
Recombinant Mouse FAS/CD95 protein expressed by Mammalian
Target
Apt; APO; Tumor necrosis factor receptor superfamily member; Tnfrsf; ALPS1A; APO1; Apo-1 antigen; Apoptosis-mediating surface antigen FAS; CD95; FAS1; FASLG receptor; FASR; FASTM; Tumor necrosis factor receptor superfamily member 6; Apt1; Tnfrsf6; Fas; AI196731 Protein; APO1 Protein; APT1 Protein; CD95 Protein; lpr Protein; TNFR6 Protein; Tnfrsf6 Protein
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
WB
Purification
Antigen Affinity Purification
Concentration
1 mg/mL
Dilution
WB 1:1000-1:2000
Buffer
PBS with 0.05% proclin 300, 1% protective protein and 50% glycerol, pH7.4
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
37 kDa
Observed Molecular Weight
45 kDa
Isotype
IgG
Available Sizes
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