FAS/CD95 Polyclonal Antibody
Product Specifications
Background
Fas (CD95/APO-1) is a transmembrane glycoprotein belonging to the tumor necrosis factor (TNF) receptor superfamily. It can mediate apoptosis by ligation with an agonistic anti-Fas antibody or Fas ligand. Stimulation of Fas results in the aggregation of its intracellular death domains, leading to the formation of the death-inducing signaling complex (DISC) . FAS-mediated apoptosis may have a role in the induction of peripheral tolerance, in the antigen-stimulated suicide of mature T-cells, or both.
Abbreviation
FAS
UniProt
P25446
Host
Rabbit
Reactivity
Human
Immunogen
Recombinant Mouse FAS/CD95 protein expressed by Mammalian
Target
Apt; APO; Tumor necrosis factor receptor superfamily member; Tnfrsf; ALPS1A; APO1; Apo-1 antigen; Apoptosis-mediating surface antigen FAS; CD95; FAS1; FASLG receptor; FASR; FASTM; Tumor necrosis factor receptor superfamily member 6; Apt1; Tnfrsf6; Fas; AI196731 Protein; APO1 Protein; APT1 Protein; CD95 Protein; lpr Protein; TNFR6 Protein; Tnfrsf6 Protein
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
WB
Purification
Antigen Affinity Purification
Concentration
1 mg/mL
Dilution
WB 1:1000-1:2000
Buffer
PBS with 0.05% proclin 300, 1% protective protein and 50% glycerol, pH7.4
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
37 kDa
Observed Molecular Weight
45 kDa
Isotype
IgG
Available Sizes
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
