27-TBDMS-4-Dehydrowithaferin A
Product Specifications
UNSPSC Description
27-TBDMS-4-Dehydrowithaferin A, a withaferin A derivative, exhibits potent antiproliferative effects on the tumor cells.27-TBDMS-4-Dehydrowithaferin A induces tumor cells apoptosis. 27-TBDMS-4-Dehydrowithaferin A is a anticancer agent[1].
Target Antigen
Apoptosis
Type
Natural Products
Related Pathways
Apoptosis
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/27-tbdms-4-dehydrowithaferin-a.html
Solubility
10 mM in DMSO
Smiles
C[C@]12[C@@]3(C(C=CC2=O)=O)[C@](C[C@]4([H])[C@]1([H])CC[C@]5([C@@]4([H])CC[C@]5([H])[C@@H]([C@@]6([H])CC(C)=C(C(O6)=O)CO[Si](C)(C)C(C)(C)C)C)C)([H])O3
Molecular Weight
582.84
References & Citations
[1]Gabriel G Llanos, et al. Withaferin A-related steroids from Withania aristata exhibit potent antiproliferative activity by inducing apoptosis in human tumor cells. Eur J Med Chem. 2012 Aug;54:499-511.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-N10355/27-TBDMS-4-Dehydrowithaferin-A-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-N10355/
Clinical Information
No Development Reported
CAS Number
1214886-31-3
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