dTRIM24
Product Specifications
UNSPSC Description
dTRIM24 is a selective bifunctional degrader of TRIM24 based on PROTAC, consists of ligands for von Hippel-Lindau and TRIM24.
Target Antigen
Epigenetic Reader Domain; PROTACs
Type
Reference compound
Related Pathways
Epigenetics;PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/dTRIM24.html
Purity
99.92
Solubility
DMSO : 100 mg/mL (ultrasonic)|Ethanol : < 1 mg/mL|Methanol : 150 mg/mL (ultrasonic)
Smiles
Molecular Weight
1113.30
References & Citations
[1]Gechijian LN, et al. Functional TRIM24 degrader via conjugation of ineffectual bromodomain and VHL ligands. Nat Chem Biol. 2018 Apr;14(4):405-412.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-111519/dTRIM24-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-111519/dTRIM24-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
CAS Number
2170695-14-2
Available Sizes
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