URAT1 inhibitor 3
URAT1 inhibitor 3 is a potent, orally active, selective URAT1 inhibitor with an IC50 value of 0.8 nM. URAT1 inhibitor 3 has urate-lowering efficacy. URAT1 inhibitor 3 can be used in research of gout and hyperuricemi[1].
Product Specifications
CAS Number
[2850331-30-3]
UNSPSC
12352005
Target
URAT1
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/urat1-inhibitor-3.html
Purity
98.02
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C(C1=CC(Cl)=C(O)C(Cl)=C1)N2C=CC3=CC=CN=C32
Molecular Formula
C14H8Cl2N2O2
Molecular Weight
307.13
References & Citations
[1]Zhao Z, et, al. Discovery of novel benzbromarone analogs with improved pharmacokinetics and benign toxicity profiles as antihyperuricemic agents. Eur J Med Chem. 2022 Nov 15;242:114682.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
More Discoveries
Explore Other Products
Browse additional items from our catalog
abx414081 100 µg
Natural Cytotoxicity Triggering Receptor 1 (NCR1) Antibody
Sign In for Pricing
View Details 358784-01 48 Tests
Selenoprotein P (SEPP1) BioAssayTM ELISA Kit (Rat) discontinued
Sign In for Pricing
View Details 
358784-02 96 Tests
Selenoprotein P (SEPP1) BioAssayTM ELISA Kit (Rat) discontinued
Sign In for Pricing
View Details MBS1296681-01 0.02 mg (E-Coli)
Recombinant Vibrio vulnificus N utilization substance protein B homolog (nusB)
Sign In for Pricing
View Details