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TAT-P4- (DATC5) 2

TAT-P4- (DATC5) 2 is a high-affinity peptide inhibitor of the PICK1 (protein interacting with C kinase-1) PDZ domain, with a Ki of 1.7 nM. TAT-P4- (DATC5) 2 can inhibit addiction in rats[1].

Product Specifications

UNSPSC

12352209

Target

PKC

Type

Peptides

Related Pathways

Epigenetics; TGF-beta/Smad

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/tat-p4-datc5-2.html

Solubility

10 mM in DMSO

Smiles

[HWLKV]C(CCOCCOCC[N-RRRQRRKKRGY]CCOCCOCCC([HWLKV])=O)=O

Molecular Formula

C150H246N52O32

Molecular Weight

3289.95

References & Citations

[1]Christopher Turner, et al. Administration of a Novel High Affinity PICK1 PDZ Domain Inhibitor Attenuates Cocaine Seeking in Rats. Neuropharmacology. 2020 Mar 1;164:107901.

Shipping Conditions

Room temperature

Scientific Category

Peptides

Clinical Information

No Development Reported

Frequently Asked Questions

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