Onvatilimab

Onvatilimab (JNJ-61610588) is a human IgG1κ anti-VISTA (V-domain Ig Suppressor of T-cell Activation) monoclonal antibody. Onvatilimab can be used in colorectal cancer research[1][2].

Product Specifications

CAS Number

[1969313-51-6]

Product Name Alternative

JNJ-61610588; CI-8993; VSTB112

UNSPSC

12352203

Target

VISTA

Type

Inhibitory Antibodies

Related Pathways

Immunology/Inflammation

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/onvatilimab.html

Purity

98.00

Solubility

H2O

Smiles

[Onvatilimab]

Molecular Weight

(144.52 kDa)

References & Citations

[1]Katsiaryna Marhelava, et al. Targeting Negative and Positive Immune Checkpoints with Monoclonal Antibodies in Therapy of Cancer. Cancers (Basel) . 2019 Nov 8;11 (11) :1756. |[2]Wu L, et al. METTL3-VISTA axis-based combination immunotherapy for APC truncation colorectal cancer. J Immunother Cancer. 2024 Dec 9;12 (12) :e009865.