Onvatilimab
Onvatilimab (JNJ-61610588) is a human IgG1κ anti-VISTA (V-domain Ig Suppressor of T-cell Activation) monoclonal antibody. Onvatilimab can be used in colorectal cancer research[1][2].
Product Specifications
CAS Number
1969313-51-6
Product Name Alternative
JNJ-61610588; CI-8993; VSTB112
UNSPSC
12352203
Target
VISTA
Type
Inhibitory Antibodies
Related Pathways
Immunology/Inflammation
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/onvatilimab.html
Purity
98.00
Solubility
H2O
Smiles
[Onvatilimab]
Molecular Weight
(144.52 kDa)
References & Citations
[1]Katsiaryna Marhelava, et al. Targeting Negative and Positive Immune Checkpoints with Monoclonal Antibodies in Therapy of Cancer. Cancers (Basel) . 2019 Nov 8;11 (11) :1756. |[2]Wu L, et al. METTL3-VISTA axis-based combination immunotherapy for APC truncation colorectal cancer. J Immunother Cancer. 2024 Dec 9;12 (12) :e009865.
Shipping Conditions
Dry Ice
Storage Conditions
Store at -80°C for 2 years
Scientific Category
Inhibitory Antibodies
Clinical Information
Phase 1
Available Sizes
Frequently Asked Questions
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