Human CHAC2 Protein

<strong>Human CHAC2 Protein</strong>_x000D_ <strong>Catalog number:</strong> B2011934_x000D_ <strong>Lot number:</strong> Batch Dependent_x000D_ <strong>Expiration Date:</strong> Batch dependent_x000D_ <strong>Amount:</strong> 50 µg_x000D_ <strong>Molecular Weight or Concentration:</strong> 500 µg/mL_x000D_ <strong>Supplied as:</strong> Solution_x000D_ <strong>Applications:</strong> molecular tool for various biochemical applications_x000D_ <strong>Storage:</strong> -20 °C_x000D_ <strong>Keywords:</strong> Cation transport regulator-like protein 2 protein, ChaC protein, cation transport regulator homolog 2 protein_x000D_ <strong>Grade:</strong> Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity &gt;18 MΩ-cm) and are filtered through 0.22 um._x000D_ _x000D_ <strong>References:</strong>_x000D_ 1: Kaur A, Gautam R, Srivastava R, Chandel A, Kumar A, Karthikeyan S, Bachhawat AK. ChaC2, an Enzyme for Slow Turnover of Cytosolic Glutathione J Biol Chem. 2017 Jan 13;292(2):638-651._x000D_ 2: Nguyen YTK, Park JS, Jang JY, Kim KR, Vo TTL, Kim KW, Han BW. Structural and Functional Analyses of Human ChaC2 in Glutathione Metabolism Biomolecules. 2019 Dec 24;10(1):31._x000D_ 3: Wang CK, Yang SC, Hsu SC, Chang FP, Lin YT, Chen SF, Cheng CL, Hsiao M, Lu FL, Lu J. CHAC2 is essential for self-renewal and glutathione maintenance in human embryonic stem cells Free Radic Biol Med. 2017 Dec;113:439-451._x000D_ 4: Liu S, Fei W, Shi Q, Li Q, Kuang Y, Wang C, He C, Hu X. CHAC2, downregulated in gastric and colorectal cancers, acted as a tumor suppressor inducing apoptosis and autophagy through unfolded protein response Cell Death Dis. 2017 Aug 24;8(8):e3009._x000D_ 5: Bachhawat AK, Kaur A. Glutathione Degradation Antioxid Redox Signal. 2017 Nov 20;27(15):1200-1216._x000D_ 6: Liu G, Zeng X, Wu B, Zhao J, Pan Y. RNA-Seq analysis of peripheral blood mononuclear cells reveals unique transcriptional signatures associated with radiotherapy response of nasopharyngeal carcinoma and prognosis of head and neck cancer Cancer Biol Ther. 2020;21(2):139-146._x000D_ 7: Zhai X, Dai T, Chi Z, Zhao Z, Wu G, Yang S, Dong D. Naringin alleviates acetaminophen-induced acute liver injury by activating Nrf2 via CHAC2 upregulation Environ Toxicol. 2022 Jun;37(6):1332-1342._x000D_ 8: Wang C, Zheng W, Yao D, Chen Q, Zhu L, Zhang J, Pan Y, Zhang J, Shao C. Upregulation of DNA Metabolism-Related Genes Contributes to Radioresistance of Glioblastoma Hum Gene Ther Clin Dev. 2019 Jun;30(2):74-87._x000D_ 9: Quan K, Cao Z, Xu Q, Zhu M, Liu X, Dai M. A web-based calculator for predicting the prognosis of patients with sarcoma on the basis of antioxidant gene signatures Aging (Albany NY). 2022 Feb 10;14(3):1407-1428._x000D_ <a href="https://pubmed.ncbi.nlm.nih.gov/25385761">10: Gopalakrishnan K, Kumarasamy S, Mell B, Joe B. Genome-wide identification of long noncoding RNAs in rat models of cardiovascular and renal disease Hypertension. 2015 Jan;65(1):200-10. </a>_x000D_ _x000D_ <strong>Products Related to Human CHAC2 Protein can be found at</strong> <a href="https://moleculardepot.com/product-category/Proteins/"> Proteins</a>