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8-Aminoadenine

8-Aminoadenine is an adenine receptor ligand, with a Ki of 6.51 μM at the human binding site[1].

Product Specifications

CAS Number

[28128-33-8]

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

NAChR

Type

Reference compound

Related Pathways

Membrane Transporter/Ion Channel; Neuronal Signaling

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/8-aminoadenine.html

Purity

98.34

Solubility

1 M HCl : 0.5 mg/mL (ultrasonic; warming; heat to 60°C)

Smiles

NC1=C2N=C(N)NC2=NC=N1

Molecular Formula

C5H6N6

Molecular Weight

150.14

Precautions

H302, H315, H319, H335

References & Citations

[1]Thomas Borrmann, et al. Structure-activity relationships of adenine and deazaadenine derivatives as ligands for adenine receptors, a new purinergic receptor family. J Med Chem. 2009 Oct 8;52 (19) :5974-89.

Shipping Conditions

Blue Ice

Storage Conditions

-20°C, 3 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Curated Selection

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