8-Aminoadenine
8-Aminoadenine is an adenine receptor ligand, with a Ki of 6.51 μM at the human binding site[1].
Product Specifications
CAS Number
[28128-33-8]
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
NAChR
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel; Neuronal Signaling
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/8-aminoadenine.html
Purity
98.34
Solubility
1 M HCl : 0.5 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
NC1=C2N=C(N)NC2=NC=N1
Molecular Formula
C5H6N6
Molecular Weight
150.14
Precautions
H302, H315, H319, H335
References & Citations
[1]Thomas Borrmann, et al. Structure-activity relationships of adenine and deazaadenine derivatives as ligands for adenine receptors, a new purinergic receptor family. J Med Chem. 2009 Oct 8;52 (19) :5974-89.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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