Mc-Alanyl-Alanyl-Asparagine-PAB-MMAE
Product Specifications
UNSPSC Description
Mc-Alanyl-Alanyl-Asparagine-PAB-MMAE (compound S6) is a potent anticancer agent, which can be specific activated by tumor microenvironment. Mc-Alanyl-Alanyl-Asparagine-PAB-MMAE can suppress tumor growth in mice (extracted from patent CN104147612A)[1].
Target Antigen
Drug-Linker Conjugates for ADC
Type
Reference compound
Related Pathways
Antibody-drug Conjugate/ADC Related
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/mc-alanyl-alanyl-asparagine-pab-mmae.html
Solubility
DMSO : 180 mg/mL (ultrasonic)
Smiles
C[C@@H](C(N[C@H](C)[C@H](C1=CC=CC=C1)O)=O)[C@H]([C@@](CCC2)([H])N2C(C[C@@H](OC)[C@H]([C@@H](C)CC)N(C)C([C@H](C(C)C)NC([C@H](C(C)C)N(C)C(OCC(C=C3)=CC=C3NC([C@H](CC(N)=O)NC([C@H](C)NC([C@H](C)NC(CCCCCN(C4=O)C(C=C4)=O)=O)=O)=O)=O)=O)=O)=O)=O)OC
Molecular Weight
1316.58
References & Citations
[1]Liu Chen, et al. Tumor microenvironment specific activated micromolecular targeted conjugate and application thereof. CN104147612A.
Shipping Conditions
Room Temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-147204/Mc-Alanyl-Alanyl-Asparagine-PAB-MMAE-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-147204/Mc-Alanyl-Alanyl-Asparagine-PAB-MMAE-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
CAS Number
1638970-46-3
Available Sizes
Curated Selection
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