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5-Hydroxymethyl uridine

5-Hydroxymethyl uridine is a thymidine analogue. Analogs of this series have insertional activity towards replicated DNA. They can be used to label cells and track DNA synthesis[1].

Product Specifications

CAS Number

[30414-00-7]

UNSPSC

12352200

Hazard Statement

H315, H319, H335

Target

Nucleoside Antimetabolite/Analog

Type

Biochemical Assay Reagents

Related Pathways

Cell Cycle/DNA Damage

Applications

Cancer-programmed cell death

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/5-hydroxymethyl-uridine.html

Purity

98.0

Solubility

DMSO : 10 mg/mL (ultrasonic)

Smiles

O[C@@H]1[C@H](O)[C@@H](CO)O[C@H]1N2C(NC(C(CO)=C2)=O)=O

Molecular Formula

C10H14N2O7

Molecular Weight

274.23

Precautions

H315, H319, H335

References & Citations

[1]Cavanagh BL, et al. Thymidine analogues for tracking DNA synthesis. Molecules. 2011 Sep 15;16 (9) :7980-93.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Biochemical Assay Reagents

Clinical Information

No Development Reported

Available Sizes

Curated Selection

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