Amphimedine
Amphimedine is a polycyclic alkaloid isolated from the marine sponge Amphimedon sp. and belongs to the pyridoindole alkaloid class. Amphimedine has cytotoxic activity and has been studied as an anticancer metabolite along with neoamphimedine. Studies have shown that deoxyamphimedine damages DNA by generating reactive oxygen species, a mechanism different from that of amphimedine.
Product Specifications
CAS Number
86047-14-5
UNSPSC
12352005
Target
Reactive Oxygen Species (ROS)
Type
Natural Products
Related Pathways
Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/amphimedine.html
Smiles
O=C(C1=NC=CC2=C3C=CC=CC3=NC(C4=CC5=O)=C12)C4=CN5C
Molecular Formula
C19H11N3O2
Molecular Weight
313.31
References & Citations
[1]Deoxyamphimedine, a New Pyridoacridine Alkaloid from Two Tropical Xestospongia Sponges
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported
Frequently Asked Questions
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