CTSL/CAPN1-IN-2
CTSL/CAPN1-IN-2 (Compound 14b) is an orally active inhibitor of both CTSL and CAPN1, with IC50 values of 6.88 nM and 347.6 nM, respectively. CTSL/CAPN1-IN-2 possesses anti-inflammatory properties and favorable pharmacokinetic characteristics. CTSL/CAPN1-IN-2 exhibits broad-spectrum antiviral activity against coronaviruses by blocking viral entry[1].
Product Specifications
CAS Number
[2410075-64-6]
UNSPSC
12352005
Target
Cathepsin; SARS-CoV
Type
Reference compound
Related Pathways
Anti-infection; Metabolic Enzyme/Protease
Applications
COVID-19-anti-virus
Field of Research
Infection; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/ctsl-capn1-in-2.html
Solubility
10 mM in DMSO
Smiles
O=C(C1=CC2=CC=CC=C2O1)N[C@@H](CC3CCCCC3)C(N[C@H](C(C(NCC4=CC=CC=C4)=O)=O)C[C@H]5C(NCCC5)=O)=O
Molecular Formula
C34H40N4O6
Molecular Weight
600.70
References & Citations
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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