Diphenylamine hydrochloride
Product Specifications
UNSPSC Description
Diphenylamine hydrochloride (N-Phenylaniline hydrochloride) is an antihyperglycemic agent with oral activity and a common structure in non-steroidal anti-inflammatory drugs (NSAIDs) that uncouples oxidative phosphorylation in mitochondria, leading to a decrease in hepatic cell ATP levels and causing liver cell damage. Diphenylamine hydrochloride is also an industrial antioxidant, a dyeing mordant, and is used in agriculture as an antifungal and antibacterial agent[1][2][3][4].
Target Antigen
Bacterial; Fungal
Type
Natural Products
Related Pathways
Anti-infection
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/diphenylamine-hydrochloride.html
Purity
99.92
Solubility
DMSO : 250 mg/mL (ultrasonic)
Smiles
[H]Cl.C1(NC2=CC=CC=C2)=CC=CC=C1
Molecular Weight
205.688
References & Citations
[1]Safe S, et al. Identification of toxic impurities in commercial diphenylamine. Bull Environ Contam Toxicol. 1977 Feb;17(2):204-7.|[2]Masubuchi Y, et al. Possible mechanism of hepatocyte injury induced by diphenylamine and its structurally related nonsteroidal anti-inflammatory drugs. J Pharmacol Exp Ther. 2000 Mar;292(3):982-7.|[3]W E Alexander, et al. Metabolism of diphenylamine in the rat, rabbit and man. Food Cosmet Toxicol. 1965 Oct;3(4):571-9. |[4]M S Karawya, wt al. Diphenylamine, an antihyperglycemic agent from onion and tea. J Nat Prod. 1984 Sep-Oct;47(5):775-80.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, sealed storage, away from moisture)
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-N7133/Diphenylamine-hydrochloride-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-N7133/Diphenylamine-hydrochloride-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
CAS Number
537-67-7
Available Sizes
Curated Selection
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