Human NKp46 / NCR1 / CD335 Protein, Fc Tag
Human NKp46 Protein, Fc Tag (NC1-H5259) is expressed from human 293 cells (HEK293) . It contains AA His 129 - Thr 211 (Accession # O76036-1) .
Product Specifications
Background
Natural cytotoxicity triggering receptor 1 (NCR1) is also known as Natural killer cell p46-related protein (NK-p46), Lymphocyte antigen 94 homolog (LY94), CD antigen CD335, which belongs to the natural cytotoxicity receptor (NCR) family. NCR1 contains two Ig-like (immunoglobulin-like) domains. NCR1 interacts with CD247 and FCER1G. NCR1 / CD335 may contribute to the increased efficiency of activated natural killer (NK) cells to mediate tumor cell lysis.
Specifications
This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 35.8 kDa . The protein migrates as 40-43 kDa, 53 kDa and 60-130 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.
Accession Number
O76036-1
Expression Region
His 129 - Thr 211
Host
HEK293
Origin Species
Human
Target
NKp46
Conjugation
Unconjugated
Tag
C-Fc
Stability
● -20°C to -70°C for 12 months in lyophilized state; ● -70°C for 3 months under sterile conditions after reconstitution. For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Endotoxin
1.0 EU per μg
Purity
85%
Format
Powder
Buffer
50 mM Tris, 100 mM Glycine, 25 mM Arginine, 150 mM NaCl, pH7.5
Additives
Trehalose
Molecular Weight
35.8 kDa
Shipping Conditions
RT
Storage Conditions
-20°C
Package Size
1mg*1
Product Datasheet
Https://www.acrobiosystems.com/static/main/products/pdf/ds/NC1-H5259.pdf
Species
Human
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