Linderaspirone A
Linderaspirone A is a natural compound that can be isolated from the roots of Lindera aggregate. Linderaspirone A shows significant inhibitory effects on the production of prostaglandin E2 (PGE2), TNF-α, and IL-6 [1][2].
Product Specifications
CAS Number
1235126-46-1
UNSPSC
12352005
Target
Interleukin Related; PGE synthase
Type
Natural Products
Related Pathways
Immunology/Inflammation
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/linderaspirone-a.html
Solubility
10 mM in DMSO
Smiles
CO/C1=C/[C@H](C2=CC=CC=C2)C3(C(C(OC)=C(OC)C3=O)=O)/C(OC)=C\[C@H](C4=CC=CC=C4)C15C(C(OC)=C(OC)C5=O)=O
Molecular Formula
C34H32O10
Molecular Weight
600.61
References & Citations
[1]Lin Chen, et al. Lindera cyclopentenedione intermediates from the roots of Lindera aggregate. RSC Adv. 2018 May 16;8 (32) :17898-17904.|[2]Chi-Su Yoon, et al. Effects of Compounds Isolated from Lindera erythrocarpa on Anti-Inflammatory and Anti-Neuroinflammatory Action in BV2 Microglia and RAW264.7 Macrophage. Int J Mol Sci. 2022 Jun 27;23 (13) :7122.
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported
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