Endomorphin-1

<strong>Endomorphin-1</strong> <strong>Catalog number:</strong> MDP0703 <strong>CAS Number: </strong>N/A <strong>Sequence: </strong>Tyr-Pro-Trp-Phe-NH2 <strong>Amount:</strong> 500 ug <strong>Molecular Weight:</strong> 610.4 g/mol <strong>Supplied as:</strong> Powder <strong>Applications:</strong> molecular tool for various biochemical applications <strong>Storage:</strong> -20 °C <strong>WARNING:</strong> For in vitro Research Use Only. NOT for use on humans or animals. <strong>Grade:</strong> Biotechnology grade. All products are highly pure. <strong>References:</strong> 1: Tseng LF. The antinociceptive properties of endomorphin-1 and endomorphin-2 in the mouse Jpn J Pharmacol. 2002 Jul;89(3):216-20. 2: Pan W, Kastin AJ. From MIF-1 to endomorphin: the Tyr-MIF-1 family of peptides Peptides. 2007 Dec;28(12):2411-34. 3: Horvath G. Endomorphin-1 and endomorphin-2: pharmacology of the selective endogenous mu-opioid receptor agonists Pharmacol Ther. 2000 Dec;88(3):437-63. 4: Narita M, Ozaki S, Suzuki T. Endomorphin-induced motivational effect: differential mechanism of endomorphin-1 and endomorphin-2 Jpn J Pharmacol. 2002 Jul;89(3):224-8. 5: Sakurada S, Hayashi T, Yuhki M. Differential antinociceptive effects induced by intrathecally-administered endomorphin-1 and endomorphin-2 in mice Jpn J Pharmacol. 2002 Jul;89(3):221-3. 6: De Marco R, Janecka A. Strategies to Improve Bioavailability and In Vivo Efficacy of the Endogenous Opioid Peptides Endomorphin-1 and Endomorphin-2 Curr Top Med Chem. 2015;16(2):141-55. 7: Wu Y, Zhao X, Gan Y, Zhang X, Wei H, Wang L, Liang X, Gao X, Liu Y, Hu J, Wang Y. Original endomorphin-1 analogues exhibit good analgesic effects Bioorg Med Chem Lett. 2017 Apr 1;27(7):1557-1560. 8: Kuwana Y, Ashizawa Y, Ajima M, Nomura T, Kakeno M, Hirai S, Miura T. Micelle-associated endomorphin-1 has ability to bind copper in the oxidation state either Cu(II) or Cu(I) Arch Biochem Biophys. 2022 Sep 30;727:109305. 9: Liu H, Zhao X, Liang S, Fan L, Li Z, Zhang Y, Ni J. Amphiphilic Endomorphin-1 Derivative Functions as Self-assembling Nanomedicine for Effective Brain Delivery Chem Pharm Bull (Tokyo). 2019;67(9):977-984. <a href="https://pubmed.ncbi.nlm.nih.gov/32112361">10: LaVigne J, Keresztes A, Chiem D, Streicher JM. The endomorphin-1/2 and dynorphin-B peptides display biased agonism at the mu opioid receptor Pharmacol Rep. 2020 Apr;72(2):465-471. </a> <br><strong>Products Related to Endomorphin-1 can be found at</strong> <a href="https://moleculardepot.com/product-category/Peptides/"> Peptides</a>