Cyclo (Arg-Gly-Asp-D-Phe-Cys)
Cyclo (Arg-Gly-Asp-D-Phe-Cys) (Cyclo RGDfC), a cyclic RGD peptide which has high affinity to αvβ3, can disrupt cell integrin interactions. Cyclo (Arg-Gly-Asp-D-Phe-Cys) inhibits pluripotent marker expression in embryonic stem cells (ESCs) and the tumorigenic potential of mESCs in vivo. Cyclo (Arg-Gly-Asp-D-Phe-Cys) can be used in the research of tumors[1].
Product Specifications
CAS Number
[862772-11-0]
Product Name Alternative
Cyclo (RGDfC)
UNSPSC
12352209
Hazard Statement
H302, H315, H319
Target
Integrin
Type
Peptides
Related Pathways
Cytoskeleton
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/cyclo-arg-gly-asp-d-phe-cys.html
Purity
98.45
Solubility
DMSO : 50 mg/mL (ultrasonic)
Smiles
O=C([C@@H](CC1=CC=CC=C1)NC([C@H](CC(O)=O)NC(CNC2=O)=O)=O)N[C@@H](CS)C(N[C@H]2CCCNC(N)=N)=O
Molecular Formula
C24H34N8O7S
Molecular Weight
578.64
Precautions
H302, H315, H319
References & Citations
Shipping Conditions
Blue Ice
Storage Conditions
-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture and light, under nitrogen)
Scientific Category
Peptides
Clinical Information
No Development Reported
Isoform
αvβ3
Available Sizes
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