PDE5-IN-7
PDE5-IN-7 (compound 8) is a selective phosphodiesterase 5 (PDE 5) inhibitor with an IC50 value of 5 nM, while an IC50 of 300 nM for PDE 1[1].
Product Specifications
CAS Number
139756-21-1
UNSPSC
12352005
Hazard Statement
H315, H319, H335
Target
Phosphodiesterase (PDE)
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/pde5-in-7.html
Purity
99.83
Solubility
DMSO : 33.33 mg/mL (ultrasonic)
Smiles
O=C1C(N(C)N=C2CCC)=C2N=C(C3=CC=CC=C3OCC)N1
Molecular Formula
C17H20N4O2
Molecular Weight
312.37
Precautions
H315, H319, H335
References & Citations
[1]Haning H, et al. Imidazo[5,1-f]triazin-4 (3H) -ones, a new class of potent PDE 5 inhibitors. Bioorg Med Chem Lett. 2002 Mar 25;12 (6) :865-8. |[2]Assemat G, et al. Isolation and identification of ten new sildenafil derivatives in an alleged herbal supplement for sexual enhancement. J Pharm Biomed Anal. 2020 Nov 30;191:113482.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
PDE1; PDE5
Available Sizes
Frequently Asked Questions
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