Ceftazidime (pentahydrate) (Standard)

Ceftazidime (pentahydrate) (Standard) is the analytical standard of Ceftazidime (pentahydrate) . This product is intended for research and analytical applications. Ceftazidime (GR20263) pentahydrate , an antibiotic, has a broad spectrum activity against Gram-positive and Gram-negative aerobic bacteria. Ceftazidime pentahydrate is also active against Enterobacteriaceae (including β-lactamase-positive strains) and is resistant to hydrolysis by most β-lactamases[1].

Product Specifications

CAS Number

[78439-06-2]

Product Name Alternative

GR20263 (pentahydrate) (Standard)

UNSPSC

12352005

Target

Antibiotic; Bacterial; Beta-lactamase; Reference Standards

Type

Reference Standards

Related Pathways

Anti-infection; Others

Applications

COVID-19-immunoregulation

Field of Research

Infection; Cancer

Assay Protocol

https://www.medchemexpress.com/ceftazidime-pentahydrate-standard.html

Purity

99.15

Smiles

O=C1[C@@H](NC(/C(C2=CSC(N)=N2)=N\OC(C)(C(O)=O)C)=O)[C@@]3([H])SCC(C[N+]4=CC=CC=C4)=C(C([O-])=O)N13.[5H2O]

Molecular Formula

C22H32N6O12S2

Molecular Weight

636.65

References & Citations

[1]Richards DM, et al. Ceftazidime. A review of its antibacterial activity, pharmacokinetic properties and therapeutic use. Drugs. 1985 Feb;29 (2) :105-61.|[2]Esmat Kamali, et al. In vitro activities of cellulase and ceftazidime, alone and in combination against Pseudomonas aeruginosa biofilms. BMC Microbiol. 2021 Dec 16;21 (1) :347. |[3]Qiuxia Lin, et al. Avibactam potentiated the activity of both ceftazidime and aztreonam against S. maltophilia clinical isolates in vitro. BMC Microbiol. 2021 Feb 22;21 (1) :60. |[4]Shawn H MacVane, et al. Unexpected in vivo activity of ceftazidime alone and in combination with avibactam against New Delhi metallo-β-lactamase-producing Enterobacteriaceae in a murine thigh infection model. Antimicrob Agents Chemother. 2014 Nov;58 (11) :7007-9.