Thiamet G
Thiamet G is a potent and selective inhibitor of O-GlcNAcase (OGA), which acts to remove O-GlcNAc from modified proteins, with Ki of 20 nM for human OGA.
Product Specifications
CAS Number
[1009816-48-1]
UNSPSC
12352005
Hazard Statement
H317
Target
Autophagy; OGA
Type
Reference compound
Related Pathways
Autophagy; Neuronal Signaling
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/Thiamet-G.html
Concentration
10mM
Purity
99.99
Solubility
DMSO : 233.33 mg/mL (ultrasonic) |H2O : ≥ 50 mg/mL
Smiles
O[C@H]1[C@H](O)[C@@]2([H])N=C(NCC)S[C@@]2([H])O[C@@H]1CO
Molecular Formula
C9H16N2O4S
Molecular Weight
248.30
Precautions
H317
References & Citations
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-12588/Thiamet-G-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-12588/Thiamet-G-SDS-MedChemExpress.pdf
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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