Piperaquine

Piperaquine is a bisquinoline antimalarial agent. Piperaquine can be used in antimalarial research in combination with Artemisinin[1][2].

Product Specifications

CAS Number

[4085-31-8]

UNSPSC

12352005

Hazard Statement

H302-H315-H319-H335

Target

Parasite

Type

Reference compound

Related Pathways

Anti-infection

Applications

COVID-19-immunoregulation

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/piperaquine.html

Solubility

10 mM in DMSO

Smiles

ClC1=CC=C2C(N3CCN(CCCN4CCN(C5=CC=NC6=CC(Cl)=CC=C56)CC4)CC3)=CC=NC2=C1

Molecular Formula

C29H32Cl2N6

Molecular Weight

535.51

Precautions

P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

References & Citations

[1]Moore BR, et, al. Pharmacokinetics and pharmacodynamics of piperaquine in a murine malaria model. Antimicrob Agents Chemother. 2008 Jan; 52 (1) : 306-11.|[2]Davis TME, et, al. Piperaquine: a resurgent antimalarial drug. Drugs. 2005; 65 (1) : 75-87.