FPR1 antagonist 1
Product Specifications
UNSPSC Description
FPR1 antagonist 1 (compound 24a) is a formyl peptide receptor 1 (FPR1) antagonist with an IC50 of 25 nM. FPR1 antagonist 1 inhibits cell growth through a combined effect on cell proliferation and apoptosis and reduces cell migration, while inducing an increase in angiogenesis[1].
Target Antigen
Apoptosis; Formyl Peptide Receptor (FPR)
Type
Reference compound
Related Pathways
Apoptosis;GPCR/G Protein
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/fpr1-antagonist-1.html
Solubility
DMSO : 200 mg/mL (ultrasonic)
Smiles
CC(OC1=CC2=C(C=C1CCCCCC)C(C(C3=CC=CC=C3OC)=C(C)O2)=O)=O
Molecular Weight
408.49
References & Citations
[1]Fabio Francavilla, et al. Development of potent isoflavone-based formyl peptide receptor 1 (FPR1) antagonists and their effects in gastric cancer cell models. Eur J Med Chem. 2023 Oct 4:261:115854.
Shipping Conditions
Room Temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-156293/FPR1-antagonist-1-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-156293/FPR1-antagonist-1-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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