Me- (S, R, S) -AHPC-PEG2-OTs
Me- (S, R, S) -AHPC-PEG2-OTs is a conjugate of E3 ligase ligand and linker (E3 Ligase Ligand-Linker Conjugates) used in the synthesis of PROTAC HIF-1α degrader-1 (HY-168641) [1].
Product Specifications
CAS Number
[3033933-58-0]
UNSPSC
12352211
Target
E3 Ligase Ligand-Linker Conjugates
Type
Reference compound
Related Pathways
PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/me-s-r-s-ahpc-peg2-ots.html
Smiles
O=C(N[C@@H](C)C1=CC=C(C=C1)C2=C(N=CS2)C)[C@H]3N(C[C@@H](C3)O)C([C@H](C(C)(C)C)NCCOCCOCCOS(C4=CC=C(C=C4)C)(=O)=O)=O
Molecular Formula
C36H50N4O8S2
Molecular Weight
730.93
References & Citations
[1]Li Y, et al. Discovery of potent hypoxia-inducible factor-1α (HIF-1α) degraders by proteolysis targeting chimera (PROTAC) . Bioorg Chem. 2024 Nov 4;153:107943.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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