Me-(S,R,S)-AHPC-PEG2-OTs
Product Specifications
UNSPSC Description
Me-(S,R,S)-AHPC-PEG2-OTs is a conjugate of E3 ligase ligand and linker (E3 Ligase Ligand-Linker Conjugates) used in the synthesis of PROTAC HIF-1α degrader-1 (HY-168641)[1].
Target Antigen
E3 Ligase Ligand-Linker Conjugates
Type
Reference compound
Related Pathways
PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/me-s-r-s-ahpc-peg2-ots.html
Smiles
O=C(N[C@@H](C)C1=CC=C(C=C1)C2=C(N=CS2)C)[C@H]3N(C[C@@H](C3)O)C([C@H](C(C)(C)C)NCCOCCOCCOS(C4=CC=C(C=C4)C)(=O)=O)=O
Molecular Weight
730.93
References & Citations
[1]Li Y, et al. Discovery of potent hypoxia-inducible factor-1α (HIF-1α) degraders by proteolysis targeting chimera (PROTAC). Bioorg Chem. 2024 Nov 4;153:107943.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-168643/Me-S-R-S-AHPC-PEG2-OTs-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-168643/
Clinical Information
No Development Reported
CAS Number
3033933-58-0
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