Me- (S, R, S) -AHPC-PEG2-OTs

Me- (S, R, S) -AHPC-PEG2-OTs is a conjugate of E3 ligase ligand and linker (E3 Ligase Ligand-Linker Conjugates) used in the synthesis of PROTAC HIF-1α degrader-1 (HY-168641) [1].

Product Specifications

CAS Number

[3033933-58-0]

UNSPSC

12352211

Target

E3 Ligase Ligand-Linker Conjugates

Type

Reference compound

Related Pathways

PROTAC

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/me-s-r-s-ahpc-peg2-ots.html

Smiles

O=C(N[C@@H](C)C1=CC=C(C=C1)C2=C(N=CS2)C)[C@H]3N(C[C@@H](C3)O)C([C@H](C(C)(C)C)NCCOCCOCCOS(C4=CC=C(C=C4)C)(=O)=O)=O

Molecular Formula

C36H50N4O8S2

Molecular Weight

730.93

References & Citations

[1]Li Y, et al. Discovery of potent hypoxia-inducible factor-1α (HIF-1α) degraders by proteolysis targeting chimera (PROTAC) . Bioorg Chem. 2024 Nov 4;153:107943.