1-Octanol
1-Octanol (Octanol), a saturated fatty alcohol, is a T-type calcium channels (T-channels) inhibitor with an IC50 of 4 μM for native T-currents[1]. 1-Octanol is a highly attractive biofuel with diesel-like properties[2].
Product Specifications
CAS Number
111-87-5
Product Name Alternative
Octanol
UNSPSC
12352211
Hazard Statement
H227, H319, H412
Target
Calcium Channel; Endogenous Metabolite
Type
Natural Products
Related Pathways
Membrane Transporter/Ion Channel; Metabolic Enzyme/Protease; Neuronal Signaling
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Metabolic Disease; Neurological Disease
Assay Protocol
https://www.medchemexpress.com/1-octanol.html
Concentration
10mM
Purity
99.63
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
OCCCCCCCC
Molecular Formula
C8H18O
Molecular Weight
130.23
Precautions
H227, H319, H412
References & Citations
[1]Joksovic PM, et al. Mechanisms of inhibition of T-type calcium current in the reticular thalamic neurons by 1-octanol: implication of the protein kinase C pathway. Mol Pharmacol. 2010 Jan;77 (1) :87-94.|[2]Akhtar MK, et al. Microbial production of 1-octanol: A naturally excreted biofuel with diesel-like properties. Metab Eng Commun. 2014 Nov 13;2:1-5.
Shipping Conditions
Room Temperature
Storage Conditions
Store at room temperature 3 years
Scientific Category
Natural Products
Clinical Information
Phase 2
Isoform
Microbial Metabolite; T-type calcium channel
Available Sizes
Frequently Asked Questions
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