1-Octanol

1-Octanol (Octanol), a saturated fatty alcohol, is a T-type calcium channels (T-channels) inhibitor with an IC50 of 4 μM for native T-currents[1]. 1-Octanol is a highly attractive biofuel with diesel-like properties[2].

Product Specifications

CAS Number

[111-87-5]

Product Name Alternative

Octanol

UNSPSC

12352211

Hazard Statement

H227, H319, H412

Target

Calcium Channel; Endogenous Metabolite

Type

Natural Products

Related Pathways

Membrane Transporter/Ion Channel; Metabolic Enzyme/Protease; Neuronal Signaling

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Metabolic Disease; Neurological Disease

Assay Protocol

https://www.medchemexpress.com/1-octanol.html

Concentration

10mM

Purity

99.63

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

OCCCCCCCC

Molecular Formula

C8H18O

Molecular Weight

130.23

Precautions

H227, H319, H412

References & Citations

[1]Joksovic PM, et al. Mechanisms of inhibition of T-type calcium current in the reticular thalamic neurons by 1-octanol: implication of the protein kinase C pathway. Mol Pharmacol. 2010 Jan;77 (1) :87-94.|[2]Akhtar MK, et al. Microbial production of 1-octanol: A naturally excreted biofuel with diesel-like properties. Metab Eng Commun. 2014 Nov 13;2:1-5.