Fenticonazole (Nitrate)
Product Specifications
UNSPSC Description
Fenticonazole Nitrate is an antifungal imidazole ring derivative. Fenticonazole Nitrate operates via hindering ergosterol integration, and sequentially destructing the cytoplasmatic outer membrane. Fenticonazole Nitrate is effective against Gram-positive bacteria, mycoses, and vaginal candidiasis[1][2].
Target Antigen
Antibiotic; Fungal
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/Fenticonazole-Nitrate.html
Purity
98.92
Solubility
DMSO : ≥ 100 mg/mL
Smiles
[O-][N+](O)=O.ClC1=CC=C(C(OCC2=CC=C(SC3=CC=CC=C3)C=C2)CN4C=CN=C4)C(Cl)=C1
Molecular Weight
518.41
References & Citations
[1]Fernandez-Alba, J., et al., Fenticonazole nitrate for treatment of vulvovaginitis: efficacy, safety, and tolerability of 1-gram ovules, administered as ultra-short 2-day regimen. J Chemother, 2004. 16(2): p. 179-86.|[2]Rofida Albash, et al. Ultra-deformable liposomes containing terpenes (terpesomes) loaded fenticonazole nitrate for treatment of vaginal candidiasis: Box-Behnken design optimization, comparative ex vivo and in vivo studies. Drug Deliv. 2020 Dec;27(1):1514-1523.Pharmacol Res. 2021 Aug 27;105860.|Bioorg Chem. 7 October 2022, 106191.|BMC Cancer. 2024 Mar 25;24(1):371.|Molecules. 2024 Oct 15;29(20):4881.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture)
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-B0359/Fenticonazole-Nitrate-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-B0359/Fenticonazole-Nitrate-SDS-MedChemExpress.pdf
Clinical Information
Launched
CAS Number
73151-29-8
Available Sizes
Curated Selection
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