Fenticonazole (Nitrate)

Fenticonazole Nitrate is an antifungal imidazole ring derivative. Fenticonazole Nitrate operates via hindering ergosterol integration, and sequentially destructing the cytoplasmatic outer membrane. Fenticonazole Nitrate is effective against Gram-positive bacteria, mycoses, and vaginal candidiasis[1][2].

Product Specifications

CAS Number

[73151-29-8]

Product Name Alternative

REC 15-1476

UNSPSC

12352005

Hazard Statement

H360

Target

Antibiotic; Fungal

Type

Reference compound

Related Pathways

Anti-infection

Applications

COVID-19-immunoregulation

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/Fenticonazole-Nitrate.html

Concentration

10mM

Purity

98.86

Solubility

DMSO : ≥ 100 mg/mL

Smiles

[O-][N+](O)=O.ClC1=CC=C(C(OCC2=CC=C(SC3=CC=CC=C3)C=C2)CN4C=CN=C4)C(Cl)=C1

Molecular Formula

C24H21Cl2N3O4S

Molecular Weight

518.41

Precautions

H360

References & Citations

[1]Fernandez-Alba, J., et al., Fenticonazole nitrate for treatment of vulvovaginitis: efficacy, safety, and tolerability of 1-gram ovules, administered as ultra-short 2-day regimen. J Chemother, 2004. 16 (2) : p. 179-86.|[2]Rofida Albash, et al. Ultra-deformable liposomes containing terpenes (terpesomes) loaded fenticonazole nitrate for treatment of vaginal candidiasis: Box-Behnken design optimization, comparative ex vivo and in vivo studies. Drug Deliv. 2020 Dec;27 (1) :1514-1523.