Pomalidomide 4'-alkylC4-acid
Pomalidomide 4'-alkylC4-acid (linker 16) is a E3 ligase ligand-linker conjugate. Pomalidomide 4'-alkylC4-acid contains a cereblon ligand, an alkylC4 chain, and a terminal acid. Pomalidomide 4'-alkylC4-acid can be used to couple with target protein ligands to synthesize PROTAC[1].
Product Specifications
CAS Number
[2225940-48-5]
UNSPSC
12352005
Hazard Statement
H361
Target
E3 Ligase Ligand-Linker Conjugates
Type
Reference compound
Related Pathways
PROTAC
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/pomalidomide-4-alkylc4-acid.html
Purity
98.04
Solubility
DMSO : 125 mg/mL (ultrasonic)
Smiles
O=C(CCCCNC1=CC=CC(C(N2C3C(NC(CC3)=O)=O)=O)=C1C2=O)O
Molecular Formula
C18H19N3O6
Molecular Weight
373.36
Precautions
H361
References & Citations
[1]Michael Bruno Plewe, et al. Compounds and methods of treating cancers. China CN202080026538.3A. 2020-04-02
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
Cereblon
Available Sizes
Explore Other Products
Browse additional items from our catalog
Recombinant Pig Pancreatic secretory trypsin inhibitor (SPINK1)
Recombinant Pig Pancreatic secretory trypsin inhibitor (SPINK1)