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PROTAC SOS1 ligand 1

PROTAC SOS1 ligand 1, a BI-3406 analog, is a ligand for target SOS1 protein for PROTACT SIAIS562055 (HY-168637).

Product Specifications

CAS Number

3027977-34-7

UNSPSC

12352005

Target

Ligands for Target Protein for PROTAC; SOS1

Type

Reference compound

Related Pathways

MAPK/ERK Pathway; PROTAC

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/protac-sos1-ligand-1.html

Smiles

COC(C(OC1CCNCC1)=C2)=CC3=C2C(N[C@H](C)C4=CC(N)=CC(C(F)(F)F)=C4)=NC(C)=N3

Molecular Formula

C24H28F3N5O2

Molecular Weight

475.51

References & Citations

[1]Ziwei Luo, et al. Targeted Degradation of SOS1 Exhibits Potent Anticancer Activity and Overcomes Resistance in KRAS-Mutant Tumors and BCR-ABL-Positive Leukemia. Cancer Res. 2024 Oct 22.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Frequently Asked Questions

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