PROTAC SOS1 ligand 1
PROTAC SOS1 ligand 1, a BI-3406 analog, is a ligand for target SOS1 protein for PROTACT SIAIS562055 (HY-168637).
Product Specifications
CAS Number
3027977-34-7
UNSPSC
12352005
Target
Ligands for Target Protein for PROTAC; SOS1
Type
Reference compound
Related Pathways
MAPK/ERK Pathway; PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/protac-sos1-ligand-1.html
Smiles
COC(C(OC1CCNCC1)=C2)=CC3=C2C(N[C@H](C)C4=CC(N)=CC(C(F)(F)F)=C4)=NC(C)=N3
Molecular Formula
C24H28F3N5O2
Molecular Weight
475.51
References & Citations
[1]Ziwei Luo, et al. Targeted Degradation of SOS1 Exhibits Potent Anticancer Activity and Overcomes Resistance in KRAS-Mutant Tumors and BCR-ABL-Positive Leukemia. Cancer Res. 2024 Oct 22.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog