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Capeserod (hydrochloride)

Capeserod hydrochloride (SL65.0155) is a 5-HT4 (e) receptor partial agonist (Ki=0.6 nM) with potent cognitive enhancing properties. Capeserod hydrochloride acts as a partial agonist in cells expressing 5-HT4 (b) and 5-HT4 (e) splice variants, stimulating cAMP production with IC50 values of 244 and 29 nM, respectively. Capeserod hydrochloride is used in the study of memory impairment and dementia[1].

Product Specifications

CAS Number

191023-43-5

Product Name Alternative

SL65.0155

UNSPSC

12352005

Target

5-HT Receptor

Type

Reference compound

Related Pathways

GPCR/G Protein; Neuronal Signaling

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/capeserod-hydrochloride.html

Smiles

O=C1OC(C2=C3OCCOC3=C(N)C(Cl)=C2)=NN1C4CCN(CC4)CCC5=CC=CC=C5.Cl

Molecular Formula

C23H26Cl2N4O4

Molecular Weight

493.38

References & Citations

[1]Moser P C, et al. SL65. 0155, a novel 5-hydroxytryptamine4 receptor partial agonist with potent cognition-enhancing properties[J]. Journal of Pharmacology and Experimental Therapeutics, 2002, 302 (2) : 731-741.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

5-HT4 Receptor; Apolipoprotein D

Frequently Asked Questions

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