Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

Gallinamide A (TFA)

Gallinamide A TFA is a linearly depositing peptide and a potent inhibitor of cathepsin L (CatL) (IC50: 17.6 pM) . Gallinamide A TFA inhibits SARS-CoV-2 infection by inhibiting CatL (EC50: 28 nM) . Gallinamide A TFA also inhibits Plasmodium falciparum (IC50: 50 nM) [1][2].

Product Specifications

CAS Number

1352920-57-0

UNSPSC

12352005

Target

Cathepsin; Parasite; SARS-CoV

Type

Natural Products

Related Pathways

Anti-infection; Metabolic Enzyme/Protease

Applications

COVID-19-anti-virus

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/gallinamide-a-tfa.html

Purity

99.85

Solubility

10 mM in DMSO

Smiles

CC[C@H](C)[C@H](N(C)C)C(O[C@@H](CC(C)C)C(N[C@@H](CC(C)C)C(N[C@@H](C)/C=C/C(N1[C@H](C(OC)=CC1=O)C)=O)=O)=O)=O.OC(C(F)(F)F)=O

Molecular Formula

C33H53F3N4O9

Molecular Weight

706.79

References & Citations

[1]Ashhurst AS, et al. Potent in vitro anti-SARS-CoV-2 activity by gallinamide A and analogues via inhibition of cathepsin L. bioRxiv [Preprint]. 2020 Dec 24:2020.12.23.424111.|[2]Stoye A, et al. Falcipain Inhibitors Based on the Natural Product Gallinamide A Are Potent in Vitro and in Vivo Antimalarials. J Med Chem. 2019 Jun 13;62 (11) :5562-5578.

Shipping Conditions

Room Temperature

Storage Conditions

4°C (Powder, protect from light, stored under nitrogen)

Scientific Category

Natural Products

Clinical Information

No Development Reported

Available Sizes

Frequently Asked Questions

More Discoveries

Explore Other Products

Browse additional items from our catalog

Frozen Tissue Sections, Ovary
CS634921 5x 5 µm

Frozen Tissue Sections, Ovary

Sign In for Pricing
View Details
ACAD9 (NM_014049) Human Over-expression Lysate
LC402280 20 µg

ACAD9 (NM_014049) Human Over-expression Lysate

Sign In for Pricing
View Details
Recombinant Human PARP11 protein (His tag)
PDEH101017-01 20 µg

Recombinant Human PARP11 protein (His tag)

Sign In for Pricing
View Details
Recombinant Human PARP11 protein (His tag)
PDEH101017-02 100 µg

Recombinant Human PARP11 protein (His tag)

Sign In for Pricing
View Details
Recombinant Human PARP11 protein (His tag)
PDEH101017-03 500 µg

Recombinant Human PARP11 protein (His tag)

Sign In for Pricing
View Details
Recombinant Human PARP11 protein (His tag)
PDEH101017-04 1 mg

Recombinant Human PARP11 protein (His tag)

Sign In for Pricing
View Details