Deoxypheganomycin D

Deoxypheganomycin D is a specific antimycobacterial inhibitor with no cross-resistance to other antibiotics such as Paromomycin (HY-B0956), Capreomycin (HY-P3270), Viomycin (HY-A0155), Streptothricin (HY-129065), Kanamycin (HY-16566), and Streptomycin (HY-B1906) . Deoxypheganomycin D (28 μM) partially inhibits the growth of Mycobacterium 607, with no significant inhibitory effects on DNA, RNA, or protein synthesis. Deoxypheganomycin D (7 μM) affects leucine influx, not thymidine, and has the opposite effect on efflux. The effects of Deoxypheganomycin D may be related to cell membrane and specific mycobacterial lipid components.

Product Specifications

CAS Number

[69280-94-0]

UNSPSC

12352005

Target

Antibiotic; Bacterial

Type

Reference compound

Related Pathways

Anti-infection

Applications

COVID-19-immunoregulation

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/deoxypheganomycin-d.html

Smiles

OC(C[C@@H](C(O)=O)NC([C@H](CCCCN)NC([C@H](C(C)(C)C)NC([C@H](CC(N)=O)NC([C@H](C1=CC(O)=C(C(O)=C1)C)NC(N)=N)=O)=O)=O)=O)=O

Molecular Formula

C30H47N9O11

Molecular Weight

709.75

References & Citations

[1]Suzukake-Tsuchiya K, et al. Mode of action of deoxypheganomycin D on Mycobacterium smegmatis ATCC 607. J Antibiot (Tokyo) . 1988 May;41 (5) :675-83.