Apelin-36 (Human, 1-16 Amide)

<strong>Apelin-36 (Human, 1-16 Amide)</strong> <strong>Catalog number:</strong> MDP0832 <strong>CAS Number: </strong>177966-56-2 <strong>Sequence: </strong>Leu-Val-Gln-Pro-Arg-Gly-Ser-Arg-Asn-Gly-Pro-Gly-Pro-Trp-Gln-Gly-NH2 <strong>Amount:</strong> 100 ug <strong>Molecular Weight:</strong> 1704.8 g/mol <strong>Supplied as:</strong> Powder <strong>Applications:</strong> molecular tool for various biochemical applications <strong>Storage:</strong> -20 °C <strong>WARNING:</strong> For in vitro Research Use Only. NOT for use on humans or animals. <strong>Grade:</strong> Biotechnology grade. All products are highly pure. <strong>References:</strong> 1: Gürlek B, Yılmaz A, Durakoğlugil ME, Karakaş S, Kazaz İM, Önal Ö, Şatıroğlu Ö. Evaluation of serum apelin-13 and apelin-36 concentrations in preeclamptic pregnancies J Obstet Gynaecol Res. 2020 Jan;46(1):58-65. 2: Aslan M, Celik O, Celik N, Turkcuoglu I, Yilmaz E, Karaer A, Simsek Y, Celik E, Aydin S. Cord blood nesfatin-1 and apelin-36 levels in gestational diabetes mellitus Endocrine. 2012 Jun;41(3):424-9. 3: Nyimanu D, Kuc RE, Williams TL, Bednarek M, Ambery P, Jermutus L, Maguire JJ, Davenport AP. Apelin-36-[L28A] and Apelin-36-[L28C(30kDa-PEG)] peptides that improve diet induced obesity are G protein biased ligands at the apelin receptor Peptides. 2019 Nov;121:170139. 4: Sakamoto K, Murakami Y, Sawada S, Ushikubo H, Mori A, Nakahara T, Ishii K. Apelin-36 is protective against N-methyl-D-aspartic-acid-induced retinal ganglion cell death in the mice Eur J Pharmacol. 2016 Nov 15;791:213-220. 5: He Q, Wang Y, Yang H, Wang J, Zhang J, Liu D. Apelin‑36 protects against lipopolysaccharide‑induced acute lung injury by inhibiting the ASK1/MAPK signaling pathway Mol Med Rep. 2021 Jan;23(1):6. 6: Zhu J, Dou S, Jiang Y, Bai B, Chen J, Wang C, Cheng B. Apelin-36 exerts the cytoprotective effect against MPP(+)-induced cytotoxicity in SH-SY5Y cells through PI3K/Akt/mTOR autophagy pathway Life Sci. 2019 May 1;224:95-108. 7: Zhu J, Gao W, Shan X, Wang C, Wang H, Shao Z, Dou S, Jiang Y, Wang C, Cheng B. Apelin-36 mediates neuroprotective effects by regulating oxidative stress, autophagy and apoptosis in MPTP-induced Parkinson's disease model mice Brain Res. 2020 Jan 1;1726:146493. 8: Yamaleyeva LM, Chappell MC, Brosnihan KB, Anton L, Caudell DL, Shi S, McGee C, Pirro N, Gallagher PE, Taylor RN, Merrill DC, Mertz HL. Downregulation of apelin in the human placental chorionic villi from preeclamptic pregnancies Am J Physiol Endocrinol Metab. 2015 Nov 15;309(10):E852-60. 9: Aydin S. The presence of the peptides apelin, ghrelin and nesfatin-1 in the human breast milk, and the lowering of their levels in patients with gestational diabetes mellitus Peptides. 2010 Dec;31(12):2236-40. <a href="https://pubmed.ncbi.nlm.nih.gov/19597036">10: Maguire JJ, Kleinz MJ, Pitkin SL, Davenport AP. [Pyr1]apelin-13 identified as the predominant apelin isoform in the human heart: vasoactive mechanisms and inotropic action in disease Hypertension. 2009 Sep;54(3):598-604. </a> <br><strong>Products Related to Apelin-36 (Human, 1-16 Amide) can be found at</strong> <a href="https://moleculardepot.com/product-category/Peptides/"> Peptides</a>