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EcDsbB-IN-9

EcDsbB-IN-9 (Compound 9) is a potent E. coli DsbB (EcDsbB) inhibitor with an IC50 of 1.7 μM and a Ki of 46 nM[1].

Product Specifications

CAS Number

41933-33-9

Product Name Alternative

9-Amino-20(S)-camptothecin; 9-Amino-CPT

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

Bacterial

Type

Reference compound

Related Pathways

Anti-infection

Applications

COVID-19-immunoregulation

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/ecdsbb-in-9.html

Concentration

10mM

Purity

97.0

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

O=C1C(Cl)=C(C=NN1CC2=CC=CC=C2)Cl

Molecular Formula

C11H8Cl2N2O

Molecular Weight

255.10

Precautions

H302, H315, H319, H335

References & Citations

[1]Landeta C, et al. Compounds targeting disulfide bond forming enzyme DsbB of Gram-negative bacteria. Nat Chem Biol. 2015 Apr;11 (4) :292-8.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Frequently Asked Questions

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