EcDsbB-IN-9
EcDsbB-IN-9 (Compound 9) is a potent E. coli DsbB (EcDsbB) inhibitor with an IC50 of 1.7 μM and a Ki of 46 nM[1].
Product Specifications
CAS Number
41933-33-9
Product Name Alternative
9-Amino-20(S)-camptothecin; 9-Amino-CPT
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Bacterial
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/ecdsbb-in-9.html
Concentration
10mM
Purity
97.0
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C1C(Cl)=C(C=NN1CC2=CC=CC=C2)Cl
Molecular Formula
C11H8Cl2N2O
Molecular Weight
255.10
Precautions
H302, H315, H319, H335
References & Citations
[1]Landeta C, et al. Compounds targeting disulfide bond forming enzyme DsbB of Gram-negative bacteria. Nat Chem Biol. 2015 Apr;11 (4) :292-8.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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