Ganoderic acid A
Ganoderic acid A can inhibit of the JAK-STAT3 signaling pathway, also inhibit proliferation, viability, ROS.
Product Specifications
CAS Number
81907-62-2
UNSPSC
12352211
Target
Apoptosis; Autophagy; Endogenous Metabolite
Type
Natural Products
Related Pathways
Apoptosis; Autophagy; Metabolic Enzyme/Protease
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/Ganoderic-acid-A.html
Purity
99.84
Solubility
DMSO : 62.5 mg/mL (ultrasonic) |Ethanol : ≥ 50 mg/mL
Smiles
CC1(C)C(CC[C@]2(C)C3=C([C@@]4([C@@H](O)C[C@@H]([C@]4(CC3=O)C)[C@H](C)CC(C[C@@H](C)C(O)=O)=O)C)[C@@H](O)C[C@@]12[H])=O
Molecular Formula
C30H44O7
Molecular Weight
516.67
References & Citations
[1]Radwan FF et al. Reduction of myeloid-derived suppressor cells and lymphoma growth by a natural triterpenoid. J Cell Biochem. 2015 Jan;116 (1) :102-14.|[2]Yao X et al. Inhibition of the JAK-STAT3 signaling pathway by ganoderic acid A enhances chemosensitivity of HepG2 cells to cisplatin.
 Planta Med. 2012 Nov;78 (16) :1740-8.|[3]Gill BS et al. Evaluating anti-oxidant potential of ganoderic acid A in STAT 3 pathway in prostate cancer. Mol Biol Rep. 2016 Sep 17.|[4]Shao J et al. [Ganoderic acid A suppresses proliferation and invasion and induces apoptosis in human osteosarcoma cells]. Nan Fang Yi Ke Da Xue Xue Bao. 2015 May;35 (5) :619-24.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture and light)
Scientific Category
Natural Products
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
GTR15231967 1 Vial
Lentiviral mouse Slc22a28 shRNA (UAS) - Lentiviral mouse Slc22a28 shRNA (UAS) plasmid
Sign In for Pricing
View Details 
MBS9511628-01 3 mL (RTU)
Anti-Human Factor XIIIa (ABT515) Mouse Monoclonal Antibody (Ready to Use)
Sign In for Pricing
View Details MBS9511628-02 6 mL (RTU)
Anti-Human Factor XIIIa (ABT515) Mouse Monoclonal Antibody (Ready to Use)
Sign In for Pricing
View Details MBS9511628-03 12 mL (RTU)
Anti-Human Factor XIIIa (ABT515) Mouse Monoclonal Antibody (Ready to Use)
Sign In for Pricing
View Details MBS9511628-04 5x 12 mL (RTU)
Anti-Human Factor XIIIa (ABT515) Mouse Monoclonal Antibody (Ready to Use)
Sign In for Pricing
View Details A04926-1-APC 100 µg/Vial
Anti-SLC14A1/UTE Antibody Picoband®, APC Conjugate
Sign In for Pricing
View Details