Recombinant Human Alpha Crystallin A

Product Specifications

CAS Number

9000-83-3

Product Name Alternative

CRYAA

UniProt

P02489

Reactivity

Human

Target Antigen

Alpha Crystallin A

Target

Alpha Crystallin A

Type

Protein

Applications

Concentration

Lot Specific

Dilution

Dilute in PBS or medium that is identical to that used in the assay system.

Form

Liquid

Buffer

20 mM Tris

Storage Conditions

Store at 4°C if entire vial will be used within 2-4 weeks. Store at or below -20°C for longer periods of time. For long term storage, addition of a carrier protein (0.1% HSA or BSA) is recommended.

Specificity

Alpha Crystallin A

Formulation

Sterile-filtered colorless solution contains 20mM Tris-HCl, pH 7.5, 50mM NaCl and 1mM EDTA.

Buffer pH

pH 7.5

Target Background

Alpha crystallins are composed of two gene products: alpha-A (acidic) and alpha-B (basic). Alpha crystallins are induced by heat shock and are members of the small heat shock protein family. They act as molecular chaperones. In addition, alpha crystallins have autokinase activity and play a role in intracellular architecture. The expression of alpha crystalline A is preferentially restricted to lens cells.