Anti-Mouse CD22 Antibody (Cy34.1)

Anti-Mouse CD22 Antibody (Cy34.1) is a mouse-derived IgG1 κ type antibody inhibitor, targeting to mouse CD22. Anti-Mouse CD22 Antibody (Cy34.1) can deplete CD22 cells and B cells. Anti-Mouse CD22 Antibody (Cy34.1) can promote microglial phagocytosis. Anti-Mouse CD22 Antibody (Cy34.1) can be used for the researches of inflammation and neurological disease, such as Alzheimer's disease (AD) and neuromyelitis[1][2][3].

Product Specifications

CAS Number

[9007-83-4]

UNSPSC

12352203

Hazard Statement

H302, H315, H319, H335

Target

CD22

Type

Inhibitory Antibodies

Related Pathways

Immunology/Inflammation

Field of Research

Inflammation/Immunology; Neurological Disease

Assay Protocol

https://www.medchemexpress.com/anti-mouse-cd22-antibody-cy34-1.html

Purity

Solubility

10 mM in DMSO

Smiles

[Anti-MouseCD22Antibody(Cy34.1)]

Molecular Weight

(150 kDa)

Precautions

H302, H315, H319, H335

References & Citations

[1]Säwén P, et al. Mitotic History Reveals Distinct Stem Cell Populations and Their Contributions to Hematopoiesis. Cell Rep. 2016 Mar 29;14 (12) :2809-18.|[2]Pluvinage JV, et al. CD22 blockade restores homeostatic microglial phagocytosis in ageing brains. Nature. 2019 Apr;568 (7751) :187-192.|[3]Zhang W, et al. CD22 blockade exacerbates neuroinflammation in Neuromyelitis optica spectrum disorder. J Neuroinflammation. 2024 Nov 30;21 (1) :313.