Saredutant
Saredutant is a selective NK2 receptor antagonist.
Product Specifications
CAS Number
142001-63-6
Product Name Alternative
SR 48968; SR 48968C
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Neurokinin Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease; Endocrinology
Assay Protocol
https://www.medchemexpress.com/Saredutant.html
Concentration
10mM
Purity
98.09
Solubility
DMSO : 250 mg/mL (ultrasonic)
Smiles
CC(NC1(C2=CC=CC=C2)CCN(CC[C@@H](C3=CC(Cl)=C(Cl)C=C3)CN(C)C(C4=CC=CC=C4)=O)CC1)=O
Molecular Formula
C31H35Cl2N3O2
Molecular Weight
552.53
Precautions
H302, H315, H319, H335
References & Citations
[1]Overstreet DH, et al. Saredutant, an NK2 receptor antagonist, has both antidepressant-like effects and synergizes with Desipramine in an animal model of depression. Pharmacol Biochem Behav. 2010 Aug;96 (2) :206-10.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
Phase 3
Isoform
NK2R
Available Sizes
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