Saredutant

Saredutant is a selective NK2 receptor antagonist.

Product Specifications

CAS Number

[142001-63-6]

Product Name Alternative

SR 48968; SR 48968C

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

Neurokinin Receptor

Type

Reference compound

Related Pathways

GPCR/G Protein; Neuronal Signaling

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease; Endocrinology

Assay Protocol

https://www.medchemexpress.com/Saredutant.html

Concentration

10mM

Purity

98.09

Solubility

DMSO : 250 mg/mL (ultrasonic)

Smiles

CC(NC1(C2=CC=CC=C2)CCN(CC[C@@H](C3=CC(Cl)=C(Cl)C=C3)CN(C)C(C4=CC=CC=C4)=O)CC1)=O

Molecular Formula

C31H35Cl2N3O2

Molecular Weight

552.53

Precautions

H302, H315, H319, H335

References & Citations

[1]Overstreet DH, et al. Saredutant, an NK2 receptor antagonist, has both antidepressant-like effects and synergizes with Desipramine in an animal model of depression. Pharmacol Biochem Behav. 2010 Aug;96 (2) :206-10.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

Phase 3

Isoform

NK2R

Available Sizes

Curated Selection

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