Patent Blue V (calcium salt)

Patent Blue V calcium salt is a triarylmethane dye used for tissue staining and lymphatic tracing, mainly applied by topical injection or eye drops. Patent Blue V calcium salt has affinity for specific tissues (such as corneal endothelium, lymphatic system), and stains the target structure by adsorption or binding, assisting in precise operation during surgery. Patent Blue V calcium salt is mainly used in ophthalmic surgery (such as graft staining for Descemet's membrane endothelial keratoplasty) and lymphatic drainage localization for sentinel lymph node biopsy of tumors[1][2].

Product Specifications

CAS Number

[3536-49-0]

UNSPSC

12171500

Hazard Statement

H302, H315, H319, H335

Target

Fluorescent Dye

Type

Dye Reagents

Related Pathways

Others

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/patent-blue-v-calcium-salt.html

Purity

99.99

Solubility

DMSO : 100 mg/mL (ultrasonic; warming; heat to 60°C)

Smiles

CC/[N+](CC)=C1C=C/C(C=C/1)=C(C2=CC=C(N(CC)CC)C=C2)\C3=CC(O)=C(S(=O)([O-])=O)C=C3S(=O)([O-])=O.[Ca+2].[1/2]

Molecular Formula

C27H32N2O7S2.1/2Ca

Molecular Weight

580.72

Precautions

H302, H315, H319, H335

References & Citations

[1]Shin-Yi Chen, et al. Patent Blue V as an Alternative Stain for DMEK Grafts: Safety, Stain Retention, and Feasibility. Cornea. 2019 Oct;38 (10) :1322-1327.|[2]McTaggart MP, et al. Effect of Patent Blue V (®) dye on sample interference indices on the Abbott Architect. Ann Clin Biochem. 2012 Sep;49 (Pt 5) :510-1.|[3]Scherer K, et al. Anaphylaxis to isosulfan blue and cross-reactivity to patent blue V: case report and review of the nomenclature of vital blue dyes. Ann Allergy Asthma Immunol. 2006 Mar;96 (3) :497-500.