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Ccc_R08

Ccc_R08 is a non-cytotoxic and orally active cccDNA inhibitor that reduces cccDNA levels in the liver of HBV-infected mice. ccc_R08 can be used in the study of HBV virus (hepatitis B virus) infection[1][2].

Product Specifications

CAS Number

2919019-72-8

UNSPSC

12352005

Target

DNA/RNA Synthesis; HBV

Type

Reference compound

Related Pathways

Anti-infection; Cell Cycle/DNA Damage

Applications

COVID-19-anti-virus

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/ccc-r08.html

Concentration

10mM

Purity

98.87

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

O=C1C=C(C2=CC=C(OCCOC3CC(C(O)=O)C3)C=C2)OC4=C1C=CC=C4Cl

Molecular Formula

C22H19ClO6

Molecular Weight

414.84

References & Citations

[1]Wang L, et al. Discovery of a first-in-class orally available HBV cccDNA inhibitor. J Hepatol. 2022 Dec 29:S0168-8278 (22) 03466-3. |[2]Ligat G, et al. Targeting Viral cccDNA for Cure of Chronic Hepatitis B. Curr Hepatol Rep. 2020 Sep;19 (3) :235-244.

Shipping Conditions

Room Temperature

Storage Conditions

4°C (Powder, sealed storage, away from moisture and light)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Frequently Asked Questions

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