Tin protoporphyrin IX dichloride
Tin protoporphyrin IX dichloride (SnPPIX) is a potent Heme oxygenase-1 (HO-1) inhibitor. Tin protoporphyrin IX dichloride sensitizes pancreatic ductal adenocarcinoma (PDAC) tumors to chemotherapy in mice model[1].
Product Specifications
CAS Number
[14325-05-4]
Product Name Alternative
Tin-protoporphyrin IX; Sn-Protoporphyrin; SnPPIX
UNSPSC
12352005
Hazard Statement
H315, H319, H335
Target
Reactive Oxygen Species (ROS)
Type
Reference compound
Related Pathways
Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/tin-protoporphyrin-ix-dichloride.html
Purity
96.2
Solubility
0.1 M NaOH : 12.5 mg/mL (ultrasonic) |1M NaOH : 5 mg/mL (ultrasonic) |DMSO : 0.5 mg/mL (ultrasonic; warming)
Smiles
[Cl-][Sn+4]123([N-]4C5=C(CCC(O)=O)C(C)=C4C=C(C(C=C)=C6C)[N]1=C6C=C(C(C=C)=C7C)[N-]2C7=CC(C(C)=C8CCC(O)=O)=[N]3C8=C5)[Cl-]
Molecular Formula
C34H32Cl2N4O4Sn
Molecular Weight
750.26
Precautions
H315, H319, H335
References & Citations
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, sealed storage, away from moisture)
Scientific Category
Reference compound1
Clinical Information
Phase 2
Available Sizes
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